Comprehensive Summary
This paper, presented by Sun et al., investigates the research development of retinal vein occlusion. Retinal vein occlusion is a major disease that can impact the retinal venous system, which can lead to many complications. Due to its known nature for developing into more severe issues as well as its prevalence across all races, many studies have been centered around learning more about retinal vein occlusion. The paper investigates the number of publications as well as who, where, and what keywords are associated with each publication. The study examined 4848 publications from Web of Science Core Collection and found that the annual publication number increased, demonstrating that more researchers are interested in retinal vein occlusion. The United States and France were found to publish the most papers, with the University of California, Los Angeles being the most active organization to conduct research on this topic. Additionally, Retina and Ophthalmology were found to be the most prolific and contain the most important information regarding this condition. Furthermore, the study found that most studies were concentrated around risk factors, pathogenesis, ocular treatments, and imaging diagnosis. Concerning risk factors, the study found that retinal vein occlusion has demonstrated correlation with increasing age. There has been much significant development among treatments, as most of the research focuses on treatment plans for complications that arise. With regards to imaging diagnosis, the rapid technological developments, specifically LLM, have helped with prognosis and treatment strategies.
Outcomes and Implications
Sun et al. in this study examines the progress of literature and research with regards to retinal vein occlusion. The paper has highlighted the increasing prevalence of research surrounding this condition, implying more importance has been put onto retinal vein occlusion. By listing the most prolific countries and institutions that produce research regarding retinal vein occlusion, the paper can support collaborations between researchers interested in retinal vein occlusion with institutions and countries that put a lot of resources into this topic. Furthermore, By finding the keywords associated with the many papers, Sun et al. demonstrates where most of the research is being conducted on. This can help indicate future directions for research as topics such as diagnosis and pathogenesis appear to have developments and findings through the research. With regards to image diagnosis, the paper suggests that future research be directed towards implementing deep learning and AI into image analysis and image techniques to assist with diagnosis and prognosis. However, the paper suggests most research should be focused on treatment plans, as no major findings have been noted yet with regards to treating the occlusion that arises as a result of retinal vein occlusion. The overall meta-analysis demonstrates the significant developments of research regarding retinal vein occlusion, but still indicates that there are many topics and questions that remain unanswered.