Neurotechnology

Comprehensive Summary

This paper, presented by Ghasemi et al., examines the use of a scalp EEG-based ensemble of convolutional neural networks (CNN) to identify obsessive-compulsive disorder (OCD). The three advanced CNN models of interest were EEGNet, Shallow ConvNet, and Deep ConvNet as they have yet to be used in diagnosing OCD although they are trained on EEG datasets. The researchers used these models designed for scalp-EEG data analysis and optimized them using the Differential Evolution algorithm to improve the accuracy of diagnosis. To produce input images for the CNN models, an electroencephalogram (EEG) segmentation approach was used. 2880 images from 6 participants were used as the final test data. After the models were trained and optimized, the test data was used to evaluate their performance in metrics such as accuracy, sensitivity, specificity, F1-score, AUC, and confusion matrix. EEG patterns were used to distinguish between individuals with OCD and healthy individuals. Among the individual models, Shallow ConvNet outperformed the rest with an accuracy of 85.91 ± 0.72, sensitivity of 82.19 ± 0.72, specificity of 93.34 ± 2.91, F1-score of 88.61 ± 0.49, AUC of 87.77 ± 0.12, and PAM of 74.89 ± 1.36. Furthermore, the ensemble of the three scalped EEG-based CNNs performed extremely well with an accuracy of 87.03 ± 0.46, sensitivity of 82.21 ± 0.56, specificity of 96.69 ± 1.28, F1-score of 89.42 ± 0.37, and AUC of 89.45 ± 0.06. These findings show that EEG-based CNN models, particularly ensembles, may be able to improve the detection of OCD with high accuracy and specificity.

Outcomes and Implications

Early and accurate diagnoses of OCD are vital to ensure that patients receive timely treatment and the costs of treatment are minimized for both patients and medical facilities. Using deep learning with CNN models trained on EEG signals could provide clinicians with a more objective and reliable diagnostic tool, particularly in complex cases in which traditional clinical evaluations may need to be supplemented. While the study is limited by a smaller sample size and lack of accountability for patient demographics and severity level, Ghasemi et al underscored the importance of further validation of the generalizability of the model by conducting further studies among multiple datasets and conditions. Their intent to work with clinicians to examine the validity of their results in clinical settings will aid in ensuring its clinical relevance and potential as an OCD diagnostic tool.

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© 2025 AIIM. Created by AIIM IT Team

AIIM Research

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© 2025 AIIM. Created by AIIM IT Team