Nwalieji et al.'s study focuses on improving ways to engage youth in Africa through research mentorship programs that enhance the practice of evidence-based medicine and expand opportunities for academic and professional growth in students. The research was conducted by examining mentorship programs implemented across West, East, and Southern Africa. Nwalieji et al assessed various structural barriers such as “brain drain”, limited funding, and inadequate research infrastructure. Additionally, they evaluated the integration of region-specific strategies, including fellowships, tiered mentorship models, AI tools, and international exchange programs that can help strengthen mentorship and scientific leadership opportunities for students. The findings of Nwalieji et al.’s analysis show that mentorship programs across Africa are unevenly distributed, underfunded, and limited by the lack of institutional support. CARTA, AMARI, THET, and MEPI-MESAU are existing programs that support young researchers through mentorship and professional development. However, the study found that these initiatives are often only concentrated in urban areas within well funded institutions. This suggests that a one-size-fits-all approach to mentorship is inadequate, as these programs must account for the uneven distribution of resources and gaps in education across each region. Furthermore, they highlight the importance of integrating grant writing and research training into undergraduate and graduate health programs, in order for students to make informed decisions early on in their academic careers. Overall, Nwalieji et al. emphasize that effective mentorship initiatives need to build on local communities and address their specific needs.