The paper written by Solomonov discusses how psychotherapy should move past a “one size fits all” approach and instead be tailored to an individual's needs instead. The author emphasizes identifying and targeting the mechanisms of change, including the specific biological, cognitive, emotional, or behavioral processes that drive improvement in therapy. By focusing on these mechanisms, clinicians can match interventions to each patient’s unique profile, increasing effectiveness and efficiency. The paper also highlights the need to make these precision-based approaches accessible in community settings, where resources are limited and populations are diverse. To achieve this, researchers must develop simple, scalable interventions, improve real-world measurement tools, and collaborate across disciplines to bridge science and practice. Overall, the article calls for a shift from asking “what treatment works” to “for whom and why it works,” paving the way for more equitable, personalized mental-health care.